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MSS mismatch

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Dear forum,

I have successfully created a site to site VPN to Azure via our Nokia Checkpoint IP350 firewall. I understand this device is not on the list of supported firewalls however we have managed to get the tunnel up and work with Azure.  The problem I have is with a Windows Server 2012 VM in Azure which has been promoted to domain controller - I am getting intermittent RPC failures which is causing the DC to fail replication.  

I have since found out that the firewall we are using has a default MSS of 1640 and not the recommended size of 1350.   Can someone explain the consequences of this mis match and might this be the cause of my problems to sucessfully get my domain controller to work?  the failures are not restirctions on permitted ports over the tunnel or other firewalls - these condtions have been completely relaxed for troubleshooting.

This is preventing me from setting up a production ADFS farm for an O365 deployment.

Thanks in advance.


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